Mercedes-Benz Comand Audio / Navigation Unit 2219004804
OEM Part #: 221-900-48-04 (2219004804)
This page covers one exact OEM part number. Every unit we stocked has sold.
Programming required: this module must be coded to your VIN by a dealer or with the proper diagnostic tool before it will work.
We may be able to get another
Used OEM parts are one-of-a-kind. We sometimes get another when we dismantle a matching vehicle, but we can’t say when — browse what’s in stock now:
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This OEM COMAND AUDIO / NAVIGATION UNIT (Part Number: 2219004804) is a critical component for enhancing the multimedia and navigation experience in various Mercedes-Benz models. Designed for seamless integration, it is compatible with the S350 (2012-2013), S500 (2006-2013), S550 (2006-2013), S600 (1998-2013), S63 AMG (2006-2013), and S65 AMG (2006-2013). The unit is responsible for controlling audio and navigation functions, ensuring that you have access to real-time information and entertainment. Common issues, such as malfunctioning audio output or navigation errors, can be resolved with this genuine part, sourced directly from salvage vehicles. The installation requires programming to ensure optimal performance. This assembly significantly enhances overall vehicle functionality, making it an essential replacement for non-working units.
Specifications
| Fits Vehicle Model | S350, S400, S550, S600, S63 AMG, S65 AMG |
| Fits Vehicle Make | Mercedes-Benz |
| OEM Part No | 221-900-48-04 (2219004804) |
| Compatible OEM Part No | 221-900-29-02, 221900480428, 221-900-64-03, 221900640339, 221-900-78-02, 221-900-89-01, 221-900-90-03 |
| Category | Audio / Video |
Compatible Vehicles
Fits 30 vehicle configurations across 1 make, 2008-2013.
Check your specific vehicle before ordering.
This list shows year, make, and model. Some years have multiple trims or
engines that use different parts, and individual listings may have
additional fitment notes (e.g. “with sunroof only”). Review
the full variant list below, or
message us with your VIN
and we’ll confirm the match.
View all 30 vehicle configurations — 30 with fitment notes
| Year | Make | Model | Trim | Engine | Note |
|---|---|---|---|---|---|
| 2008 | Mercedes-Benz | S550 | Sedan | 5.5L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2008 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2008 | Mercedes-Benz | S63 AMG | Sedan | 6.3L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2008 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2009 | Mercedes-Benz | S550 | Sedan | 5.5L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2009 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2009 | Mercedes-Benz | S63 AMG | Sedan | 6.3L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2009 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2010 | Mercedes-Benz | S550 | Sedan | 5.5L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2010 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2010 | Mercedes-Benz | S63 AMG | Sedan | 6.3L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2010 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2011 | Mercedes-Benz | S550 | Sedan | 5.5L V8 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2011 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2011 | Mercedes-Benz | S63 AMG | Sedan | 5.5L V8 Turbo | PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2011 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2012 | Mercedes-Benz | S350 | Sedan | 3.0L V6 Diesel Turbo | Control assy |
| 2012 | Mercedes-Benz | S550 | Sedan | 4.7L V8 Turbo | Control assy |
| 2012 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2012 | Mercedes-Benz | S63 AMG | Sedan | 5.5L V8 Turbo | PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2012 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2013 | Mercedes-Benz | S350 | Sedan | 3.0L V6 Diesel Turbo | Control assy |
| 2013 | Mercedes-Benz | S550 | Sedan | 4.7L V8 Turbo | Control assy |
| 2013 | Mercedes-Benz | S600 | Sedan | 5.5L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2013 | Mercedes-Benz | S63 AMG | Sedan | 5.5L V8 Turbo | PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2013 | Mercedes-Benz | S65 AMG | Sedan | 6.0L V12 Turbo | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2010 | Mercedes-Benz | S400 | Sedan | 3.5L V6 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2011 | Mercedes-Benz | S400 | Sedan | 3.5L V6 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2012 | Mercedes-Benz | S400 | Sedan | 3.5L V6 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |
| 2013 | Mercedes-Benz | S400 | Sedan | 3.5L V6 | From Chassis: A 265576 From Date: 01/10/2008 Except model year: 809, PART MUST BE CHECKED AFTER INSTALLATION FOR CURRENT FLASHWARE |