Mercedes-Benz Thermostat 2722000415

OEM Part #: 272-200-04-15 (2722000415)

This page covers one exact OEM part number. Every unit we stocked has sold.

We may be able to get another

Used OEM parts are one-of-a-kind. We sometimes get another when we dismantle a matching vehicle, but we can’t say when — browse what’s in stock now:

Other Thermostat that may fit your vehicle

Thermostat / Housing 6422000215

Thermostat / Housing

$49.99
Fits 2007–2012 Mercedes-Benz
OEM: 6422000215
Used Only 1 left
  • Genuine OEM — real photos
  • 30-day returns on eligible parts
  • eBay Top Rated · 100,000+ positive ratings
  • Ships from our own indoor warehouse

The thermostat unit (OEM part number 2722000415) plays a crucial role in your vehicle's cooling system, located within the engine bay, attached to the engine block. This component regulates coolant flow, ensuring optimal engine operating temperatures. As the engine heats up, the thermostat opens to allow coolant to circulate, preventing overheating. Common issues like overheating, fluctuating temperature readings, or coolant leaks can signal the need for replacement. This thermostat is compatible with several Mercedes-Benz models, including the E350 (2006-2011), C300 (2008-2012), and GLK350 (2009-2012). Also known as a coolant thermostat, it may be referenced by alternative part numbers such as 2722030180 and 2045013782.

Specifications

Specifications for Thermostat 2722000415
Fits Vehicle ModelC230, C250, C280, C300, C350, CLK350, E350, GLK350, ML350, ML450, R350, S400, SLK280, SLK300, SLK350
Fits Vehicle MakeMercedes-Benz
OEM Part No272-200-04-15 (2722000415)
CategoryRadiator / Coolant

Compatible Vehicles

Fits 80 vehicle configurations across 1 make, 2005-2013.

Check your specific vehicle before ordering. This list shows year, make, and model. Some years have multiple trims or engines that use different parts, and individual listings may have additional fitment notes (e.g. “with sunroof only”). Review the full variant list below, or message us with your VIN and we’ll confirm the match.

Mercedes-Benz

  • C230 2006-2007 · 2 variants 2 with notes
  • C250 2012 1 with note
  • C280 2006-2007 · 2 variants 2 with notes
  • C300 2008-2012 · 5 variants 5 with notes
  • C350 2006-2012 · 8 variants 8 with notes
  • CLK350 2006-2009 · 8 variants 8 with notes
  • E350 2006-2011 · 10 variants 10 with notes
  • GLK350 2010-2012 · 3 variants 3 with notes
  • ML350 2006-2013 · 12 variants 12 with notes
  • ML450 2010-2011 · 2 variants 2 with notes
  • R350 2006-2012 · 10 variants 10 with notes
  • S400 2010-2013 · 4 variants 4 with notes
  • SLK280 2006-2008 · 3 variants 3 with notes
  • SLK300 2009-2011 · 3 variants 3 with notes
  • SLK350 2005-2011 · 7 variants 7 with notes
View all 80 vehicle configurations — 80 with fitment notes
Full vehicle fitment list for Thermostat 2722000415
Year Make Model Trim Engine Note
2005 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz C230 Sedan 2.5L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2006 Mercedes-Benz C280 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2006 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz CLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz CLK350 Coupe 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz E350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2006 Mercedes-Benz SLK280 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2006 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz C230 Sedan 2.5L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2007 Mercedes-Benz C280 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2007 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz CLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz CLK350 Coupe 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz E350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2007 Mercedes-Benz SLK280 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2007 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz C300 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2008 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz CLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz CLK350 Coupe 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz E350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2008 Mercedes-Benz SLK280 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2008 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz C300 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2009 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz CLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz CLK350 Coupe 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz E350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2009 Mercedes-Benz SLK300 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2009 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz C300 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2010 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz GLK350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz ML350 SUV 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz R350 Wagon 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz SLK300 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2010 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz C300 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2011 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz E350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz GLK350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz ML350 SUV 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz R350 Wagon 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz SLK300 Convertible 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2011 Mercedes-Benz SLK350 Convertible 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz C250 Sedan 1.8L l4 Turbo From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2012 Mercedes-Benz C300 Sedan 3.0L V6 From Engine: 30058634 From Date: 02/03/2005, From Engine: 8 From Date: 03/03/2009
2012 Mercedes-Benz C350 Coupe 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz C350 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz GLK350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz ML350 SUV 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz R350 Wagon 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz R350 Wagon 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2013 Mercedes-Benz ML350 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2013 Mercedes-Benz ML350 SUV 3.0L V6 Diesel Turbo From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz ML450 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2010 Mercedes-Benz S400 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz ML450 SUV 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2011 Mercedes-Benz S400 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2012 Mercedes-Benz S400 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005
2013 Mercedes-Benz S400 Sedan 3.5L V6 From Engine: 30058494 From Date: 02/03/2005

Ask a parts specialist

Asking about: Thermostat 2722000415 · OEM #2722000415