Mercedes-Benz Diesel Engine Oil Cooler 6421800165
OEM Part #: 642-180-01-65 (6421800165)
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Used OEM parts are one-of-a-kind. We sometimes get another when we dismantle a matching vehicle, but we can’t say when — browse what’s in stock now:
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The Diesel Engine Oil Cooler, OEM part number 6421800165, is a factory-original component essential for maintaining optimal engine temperatures in select Mercedes-Benz Sprinter models, including the 2500, 3500, and 3500XD from 2010 to 2022. Located in the engine compartment, this oil cooler efficiently circulates coolant to regulate engine oil temperature, preventing overheating and prolonging engine life. Common issues that necessitate replacement include leaks, failure to cool, or corrosion due to age. Ensure the longevity of your vehicle's performance with this genuine part, compatible with 3.0L V6 diesel engines. Other compatible models include the E320, GL320, and ML320 from 2007 to 2009.
Specifications
| Fits Vehicle Model | E320, E350, GL320, GL350, GLS350d, ML320, ML350, R320, R350, S350, Sprinter 2500, Sprinter 3500, Sprinter 3500XD, Sprinter 4500 |
| Fits Vehicle Make | Mercedes-Benz |
| OEM Part No | 642-180-01-65 (6421800165) |
| Category | Oil Pan / Pump |
Compatible Vehicles
Fits 68 vehicle configurations across 1 make, 2007-2023.
Check your specific vehicle before ordering.
This list shows year, make, and model. Some years have multiple trims or
engines that use different parts, and individual listings may have
additional fitment notes (e.g. “with sunroof only”). Review
the full variant list below, or
message us with your VIN
and we’ll confirm the match.
View all 68 vehicle configurations — 12 with fitment notes
| Year | Make | Model | Trim | Engine | Note |
|---|---|---|---|---|---|
| 2007 | Mercedes-Benz | E320 | Sedan | 3.0L V6 Diesel Turbo | 3.0 liter diesel, Oil cooler |
| 2007 | Mercedes-Benz | GL320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2007 | Mercedes-Benz | ML320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2007 | Mercedes-Benz | R320 | Wagon | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2008 | Mercedes-Benz | E320 | Sedan | 3.0L V6 Diesel Turbo | 3.0 liter diesel, Oil cooler |
| 2008 | Mercedes-Benz | GL320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2008 | Mercedes-Benz | ML320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2008 | Mercedes-Benz | R320 | Wagon | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2009 | Mercedes-Benz | E320 | Sedan | 3.0L V6 Diesel Turbo | 3.0 liter diesel, Oil cooler |
| 2009 | Mercedes-Benz | GL320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2009 | Mercedes-Benz | ML320 | SUV | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2009 | Mercedes-Benz | R320 | Wagon | 3.0L V6 Diesel Turbo | 3.0 liter diesel |
| 2010 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2010 | Mercedes-Benz | ML350 | SUV | 3.0L V6 Diesel Turbo | |
| 2010 | Mercedes-Benz | R350 | Wagon | 3.0L V6 Diesel Turbo | |
| 2010 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2010 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | E350 | Sedan | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | ML350 | SUV | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | R350 | Wagon | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2011 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | E350 | Sedan | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | ML350 | SUV | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | R350 | Wagon | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | S350 | Sedan | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2012 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | E350 | Sedan | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | ML350 | SUV | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | S350 | Sedan | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2013 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2014 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2014 | Mercedes-Benz | ML350 | SUV | 3.0L V6 Diesel Turbo | |
| 2014 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2014 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2015 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2015 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2015 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2016 | Mercedes-Benz | GL350 | SUV | 3.0L V6 Diesel Turbo | |
| 2016 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2016 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2017 | Mercedes-Benz | GLS350d | SUV | 3.0L V6 Diesel Turbo | |
| 2017 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2017 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2018 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2018 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2019 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2019 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2019 | Mercedes-Benz | Sprinter 3500XD | Van | 3.0L V6 Diesel Turbo | |
| 2019 | Mercedes-Benz | Sprinter 4500 | Van | 3.0L V6 Diesel Turbo | |
| 2020 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2020 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2020 | Mercedes-Benz | Sprinter 3500XD | Van | 3.0L V6 Diesel Turbo | |
| 2020 | Mercedes-Benz | Sprinter 4500 | Van | 3.0L V6 Diesel Turbo | |
| 2021 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2021 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2021 | Mercedes-Benz | Sprinter 3500XD | Van | 3.0L V6 Diesel Turbo | |
| 2021 | Mercedes-Benz | Sprinter 4500 | Van | 3.0L V6 Diesel Turbo | |
| 2022 | Mercedes-Benz | Sprinter 2500 | Van | 3.0L V6 Diesel Turbo | |
| 2022 | Mercedes-Benz | Sprinter 3500 | Van | 3.0L V6 Diesel Turbo | |
| 2022 | Mercedes-Benz | Sprinter 3500XD | Van | 3.0L V6 Diesel Turbo | |
| 2022 | Mercedes-Benz | Sprinter 4500 | Van | 3.0L V6 Diesel Turbo | |
| 2023 | Mercedes-Benz | Sprinter 4500 | Van | 3.0L V6 Diesel Turbo |